The Pius XII Museum is divided into two large sections: archaeology and religious art.
With regard to archaeology, there are many very interesting collections: metals (particularly a set of daggers, some of which were never used, a small statue of a gladiator, a thimble...), ceramics (from candlesticks to weights, vases, an enormous dolium, tiles, water pipelines...), coins (even recently a treasure of coins was discovered in excavations carried out in the interior cloister of the Museum), stones (from small axes to a lith, building materials, votive altars, milestones, sarcophagi, baptismal fonts, crosses...).
Religious art is also well represented by a beautiful collection of sculptures, with sculptures dating from the fourteenth century to the present, an abundant collection of paintings and a vast collection of textiles (primarily liturgical: chasubles, shoulder veils, copes, dalmatics, tabernacle curtains, chalice veils...), an important ceramic collection and a rich jewellery collection (materialised in many chalices, monstrances, cruets, altar cards...).
The collection is greatly varied, reflecting the founder's worldview of the Pius XII Museum. It is certain that each collection in the Museum has something very beautiful to conserve and to show the public.